Ketamine: Pain Management and Anesthetic Uses

Ketamine is a versatile medication used both as an anesthetic and for pain management. Its rapid-acting properties make it effective for surgical procedures, procedural sedation, and relief of acute or chronic pain.

How Ketamine Works

Ketamine works by blocking N-methyl-D-aspartate (NMDA) receptors in the brain and spinal cord, reducing nerve signal transmission. This action produces anesthesia, analgesia, and dissociative sedation while maintaining respiratory function.

Clinical Uses

• Surgical anesthesia: Provides safe and rapid induction for operations.

• Pain management: Effective for acute, chronic, and refractory pain conditions.

• Procedural sedation: Used for minor procedures requiring sedation and pain relief.

Dosage and Administration

Ketamine is typically administered intravenously or intramuscularly by trained healthcare professionals. Dosage varies depending on the patient’s condition, weight, and procedure type, with careful monitoring essential for safety.

Safety Considerations

Common side effects include dizziness, increased heart rate, and mild hallucinations. Ketamine should be administered under professional supervision with proper monitoring to avoid respiratory or cardiovascular complications.

Conclusion

Ketamine is a highly effective option for anesthesia and pain management. When used responsibly in clinical settings, it provides rapid relief, enhances patient comfort, and ensures safe procedural outcomes.