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Zafirlukast: Effective Leukotriene Receptor Blocker for Respiratory Health

Zafirlukast: Effective Leukotriene Receptor Blocker for Respiratory Health

Zafirlukast is a leukotriene receptor antagonist widely prescribed for the prevention and management of asthma symptoms. By blocking the action of leukotrienes—chemicals in the body that cause airway inflammation and constriction—zafirlukast helps improve breathing and reduce the frequency of asthma attacks.

How Zafirlukast Works

This medication works by inhibiting the binding of leukotrienes to their receptors in the lungs. As a result, it reduces swelling, decreases mucus production, and prevents airway tightening. Unlike quick-relief inhalers, zafirlukast is designed for long-term management rather than immediate symptom relief.

Common Uses

Zafirlukast is primarily used to:

  • Prevent asthma symptoms such as wheezing, coughing, and shortness of breath

  • Support long-term asthma management in both adults and children

  • Reduce the need for rescue inhalers in patients with persistent asthma

It is important to note that zafirlukast is not suitable for treating acute asthma attacks.

Dosage and Administration

Zafirlukast is usually taken orally in tablet form, often twice a day. It is recommended to take the medication on an empty stomach, either one hour before or two hours after meals, to maximize absorption. Dosage may vary depending on age, health condition, and response to treatment.

Safety and Side Effects

Most patients tolerate zafirlukast well, but possible side effects may include headache, nausea, diarrhea, or mild abdominal pain. Rare but serious side effects can involve liver function problems, so periodic monitoring may be required. Patients should follow their doctor’s guidance closely when using this medication.

Conclusion

Zafirlukast plays an important role in the long-term management of asthma by reducing airway inflammation and improving overall respiratory health. While not a rescue medication, it is highly effective as part of a daily asthma control plan. Always use zafirlukast as directed by a healthcare professional to ensure safety and effectiveness.

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